Drug Discovery Today | Vol 24, Issue 3, Pages 665-930 (March 2019)

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Editorial
1. select article Behavior, experience, skill, and training (BEST): a four-pillar framework for career development in science
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  Behavior, experience, skill, and training (BEST): a four-pillar framework for career development in science
  Rebecca Ashkenazy
  Pages 665-667
Perspective
1. Feature
  1. select article An approach towards enhancement of a screening library: The Next Generation Library Initiative (NGLI) at Bayer — against all odds?
    Mini reviewOpen access
    An approach towards enhancement of a screening library: The Next Generation Library Initiative (NGLI) at Bayer — against all odds?
    Markus Follmann, Hans Briem, Andreas Steinmeyer, Alexander Hillisch, ... Heinrich Meier
    Pages 668-672
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  2. select article When more isn’t merrier: pharmaceutical alliance networks and breakthrough innovation
    Mini reviewOpen access
    When more isn’t merrier: pharmaceutical alliance networks and breakthrough innovation
    John Qi Dong, Killian J. McCarthy
    Pages 673-677
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  3. select article Acceleration of rare disease therapeutic development: a case study of AGIL-AADC
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    Acceleration of rare disease therapeutic development: a case study of AGIL-AADC
    Sonya Das, Samuel Huang, Andrew W. Lo
    Pages 678-684
REVIEWS
1. Foundation
  1. select article Emerging role of histone deacetylase inhibitors as anti-breast-cancer agents
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    Emerging role of histone deacetylase inhibitors as anti-breast-cancer agents
    Meran Keshawa Ediriweera, Kamani Hemamala Tennekoon, Sameera Ranganath Samarakoon
    Pages 685-702
2. Keynote
  1. select article TGFβ and BMPRII signalling pathways in the pathogenesis of pulmonary arterial hypertension
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    TGFβ and BMPRII signalling pathways in the pathogenesis of pulmonary arterial hypertension
    Birger Tielemans, Marion Delcroix, Catharina Belge, Rozenn Quarck
    Pages 703-716
  2. select article Quality-by-design approach as a systematic tool for the development of nanopharmaceutical products
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    Quality-by-design approach as a systematic tool for the development of nanopharmaceutical products
    Sarwar Beg, Mahfoozur Rahman, Kanchan Kohli
    Pages 717-725
  3. select article Repurposing host-based therapeutics to control coronavirus and influenza virus
    Review articleFull text access
    Repurposing host-based therapeutics to control coronavirus and influenza virus
    Cui-Cui Li, Xiao-Jia Wang, Hwa-Chain Robert Wang
    Pages 726-736
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  4. select article Paving the way for successful islet encapsulation
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    Paving the way for successful islet encapsulation
    Nikos Dimitrioglou, Maria Kanelli, Efstathia Papageorgiou, Theodore Karatzas, Dimitris Hatziavramidis
    Pages 737-748
  5. select article Functionalized nanographene oxide in biomedicine applications: bioinspired surface modifications, multidrug shielding, and site-specific trafficking
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    Functionalized nanographene oxide in biomedicine applications: bioinspired surface modifications, multidrug shielding, and site-specific trafficking
    Hao Cheng, Khalid Gadora, Zhen Wang, Huaqing Zhang, ... Yang Ding
    Pages 749-762
3. Gene to Screen
  1. select article Characterization of circulating tumor cells as a reflection of the tumor heterogeneity: myth or reality?
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    Characterization of circulating tumor cells as a reflection of the tumor heterogeneity: myth or reality?
    Hannah K. Brown, Marta Tellez-Gabriel, Pierre-François Cartron, François M. Vallette, ... Dominique Heymann
    Pages 763-772
4. Informatics
  1. select article Artificial intelligence in drug development: present status and future prospects
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    Artificial intelligence in drug development: present status and future prospects
    Kit-Kay Mak, Mallikarjuna Rao Pichika
    Pages 773-780
  2. select article Computational modeling for formulation design
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    Computational modeling for formulation design
    Chetan Hasmukh Mehta, Reema Narayan, Usha Y. Nayak
    Pages 781-788
5. Post Screen
  1. select article The drug repurposing landscape from 2012 to 2017: evolution, challenges, and possible solutions
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    The drug repurposing landscape from 2012 to 2017: evolution, challenges, and possible solutions
    Prasanthi Polamreddy, Nandu Gattu
    Pages 789-795
  2. select article Pharmaceutical cocrystals: from serendipity to design to application
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    Pharmaceutical cocrystals: from serendipity to design to application
    Oisin N. Kavanagh, Denise M. Croker, Gavin M. Walker, Michael J. Zaworotko
    Pages 796-804
  3. select article Efficient drug discovery by rational lead hybridization based on crystallographic overlay
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    Efficient drug discovery by rational lead hybridization based on crystallographic overlay
    Shuo Zhang, Jian Zhang, Ping Gao, Lin Sun, ... Peng Zhan
    Pages 805-813
  4. select article Post-translational modification of ESKAPE pathogens as a potential target in drug discovery
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    Post-translational modification of ESKAPE pathogens as a potential target in drug discovery
    Vishvanath Tiwari
    Pages 814-822
  5. select article Hurdles in gene therapy regulatory approval: a retrospective analysis of European Marketing Authorization Applications
    Review articleOpen access
    Hurdles in gene therapy regulatory approval: a retrospective analysis of European Marketing Authorization Applications
    Marta Carvalho, Ana Paula Martins, Bruno Sepodes
    Pages 823-828
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  6. select article The use of fast photochemical oxidation of proteins coupled with mass spectrometry in protein therapeutics discovery and development
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    The use of fast photochemical oxidation of proteins coupled with mass spectrometry in protein therapeutics discovery and development
    Jing Li, Guodong Chen
    Pages 829-834
  7. select article Ultrasmall iron oxide nanoparticles: synthesis, surface modification, assembly, and biomedical applications
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    Ultrasmall iron oxide nanoparticles: synthesis, surface modification, assembly, and biomedical applications
    Cong Song, Wenjie Sun, Yunchao Xiao, Xiangyang Shi
    Pages 835-844
  8. select article Gastric-acid-mediated drug–drug interactions with direct-acting antiviral medications for hepatitis C virus infection: clinical relevance and mitigation strategies
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    Gastric-acid-mediated drug–drug interactions with direct-acting antiviral medications for hepatitis C virus infection: clinical relevance and mitigation strategies
    Guo Yu, Yi Zheng, Yichao Yu, Guo-Fu Li, Hartmut Derendorf
    Pages 845-857
  9. select article Solid nanoparticles for oral antimicrobial drug delivery: a review
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    Solid nanoparticles for oral antimicrobial drug delivery: a review
    Aun Raza, Fekade Bruck Sime, Peter J. Cabot, Faheem Maqbool, ... James Robert Falconer
    Pages 858-866
  10. select article Orphan drugs: major development challenges at the clinical stage
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    Orphan drugs: major development challenges at the clinical stage
    Diogo A. Fonseca, Inês Amaral, Ana Catarina Pinto, Maria Dulce Cotrim
    Pages 867-872
  11. select article Surface-engineered multimodal magnetic nanoparticles to manage CNS diseases
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    Surface-engineered multimodal magnetic nanoparticles to manage CNS diseases
    Asahi Tomitaka, Ajeet Kaushik, Bhavesh D. Kevadiya, Insiya Mukadam, ... Madhavan Nair
    Pages 873-882
  12. select article A unified mapping framework of multifaceted pharmacodynamic responses to hypertension interventions
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    A unified mapping framework of multifaceted pharmacodynamic responses to hypertension interventions
    Qian Wang, Jingwen Gan, Kun Wei, Scott A. Berceli, ... Rongling Wu
    Pages 883-889
  13. select article Adverse drug reactions on sexual functioning: a systematic overview
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    Adverse drug reactions on sexual functioning: a systematic overview
    Rineke Gordijn, Martina Teichert, Melianthe P.J. Nicolai, Henk W. Elzevier, Henk-Jan Guchelaar
    Pages 890-897
  14. select article Fullerene-based delivery systems
    Review articleAbstract only
    Fullerene-based delivery systems
    Houman Kazemzadeh, Masoud Mozafari
    Pages 898-905
  15. select article Drug discovery technologies to identify and characterize modulators of the pregnane X receptor and the constitutive androstane receptor
    Review articleAbstract only
    Drug discovery technologies to identify and characterize modulators of the pregnane X receptor and the constitutive androstane receptor
    Sergio C. Chai, Wenwei Lin, Yongtao Li, Taosheng Chen
    Pages 906-915
  16. select article Phosphinic acids: current status and potential for drug discovery
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    Phosphinic acids: current status and potential for drug discovery
    Moaz M. Abdou, Paul M. O’Neill, Eric Amigues, Magdalini Matziari
    Pages 916-929

Volume 24, Issue 3

Pages 665-930 (March 2019)

Actions for selected articles

Contents

Editorial

Perspective

Feature

REVIEWS

Foundation

Keynote

Gene to Screen

Informatics

Post Screen